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Moderna's omicron booster triggers stronger response against subvariants than its original shot. [View all]
This is news from a trade publication website:
Moderna's omicron booster triggers stronger response against subvariants than its original shot, company says.
Just a few weeks after the FDA recommended that COVID-19 vaccine manufactures tweak their boosters to zero in on the omicron BA.4 and BA.5 subvariants, Moderna has unveiled promising new data for its prospect.
On Monday, the mRNA specialist said its omicron-containing bivalent booster elicited higher neutralizing antibody responses compared with the current booster. After one month, trial participants who received the bivalent booster had BA.4 and BA.5 neutralizing antibodies that were 1.69 times higher than those who received the original booster, the company said.
The data has been shared with regulators and submitted for peer-reviewed publication. The company is working with regulators to advance two bivalent vaccine candidates based on various market preferences...
On Monday, the mRNA specialist said its omicron-containing bivalent booster elicited higher neutralizing antibody responses compared with the current booster. After one month, trial participants who received the bivalent booster had BA.4 and BA.5 neutralizing antibodies that were 1.69 times higher than those who received the original booster, the company said.
The data has been shared with regulators and submitted for peer-reviewed publication. The company is working with regulators to advance two bivalent vaccine candidates based on various market preferences...
My guess is that until we can vaccinate all of humanity, including those in poor countries, we are going to need regular modified boosters. Happily, this technology is flexible and we have the technical capability to fully map the protein sequences of the S-Protein quickly in order to adjust the payload RNA, but it does seem the infectiousness allows for fast evolution of the viral genome.
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