Mile 4 on Northbound US191 is in the river hollow of the Madison River. It's where you drop down the hill to where Baker's Hole campground is, Madison Arm Rd, then you cross the river and go back up out of the river hollow toward Rainbow Pt. Rd a few miles up.
I know this spot intimately, it's also very close to where that guy was mauled by that bear a year or two ago, like maybe a half mile at most only in the woods to the east of the road.
Once you drop down into the hollow, you can't see much that's far out ahead of you and, as mentioned in the article, bison fur is non-reflective, same with elk. If you can't see that little red dot that would be their eye looking right at you, you won't see them until you've hit them. It's why we try to discourage visitors from driving in YNP at night. Most locals stay home at night because of too many wildlife hazards on the road and sometimes it's the locals that hit the bison.
It's not like there are any road lights out there and it is a kind of dark that most Americans rarely see.