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SunSeeker

(57,608 posts)

9. Correct, it's not parental age, but paternal age. The Abstract clearly states the significance of paternal age.

Reply to littlemissmartypants (Reply #8)

Sat Jan 10, 2026, 03:28 AM

Saturday

Advanced parental age is a well-replicated risk factor for autism spectrum disorder (ASD), a neurodevelopmental condition with a complex and not well-defined etiology. We sought to determine parental age associations with ASD-related outcomes in subjects at high familial risk for ASD. A total of 397 younger siblings of a child with ASD, drawn from existing prospective high familial risk cohorts, were included in these analyses. Overall, we did not observe significant associations of advanced parental age with clinical ASD diagnosis, Social Responsiveness Scale, or Vineland Adaptive Behavior Scales scores. Instead, increased odds of ASD were found with paternal age < 30 years (adjusted odds ratio [AOR] = 2.83 and 95% confidence intervals [CI] = 1.14–7.02).

So yeah, it's not so much the age of the mother and father combined ("parental age" ) as it is the father's advanced age ("paternal age" ) that correlates with a several fold increase in the risk of autism.

That is probably because there's lots of men over 40 fathering babies. Look at Mick Jagger, now 82. He had his 8th child with his 5th wife in 2016. He was 73, she was 29 in 2016. Women over 40 are much less likely to be producing babies. So when you're talking about old people having babies, you're talking about men.

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Israeli scientists unlock genetic links to Autism, brain disorder using CRISPR tech -study [View all] angryxyouth Saturday OP

Will we ever learn what the dweller Saturday #1

Gene mutations in the sperm of older men. SunSeeker Saturday #3

From the study you cited: littlemissmartypants Saturday #8

Correct, it's not parental age, but paternal age. The Abstract clearly states the significance of paternal age. SunSeeker Saturday #9

Less than 30 years old does not qualify as advanced age last time I checked. littlemissmartypants Saturday #11

That is referring to the "U shaped" increase in ASD with very young fathers and old fathers (over 40). SunSeeker Saturday #12

I read the study and I don't believe it proves what you think it proves. littlemissmartypants Saturday #14

They're not assumptions. I gave you 2 additional studies that found old paternal age increases autism risk. SunSeeker Yesterday #15

My niece has autism. ananda 22 hrs ago #16

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An NIH study found that children with autism are less likely to be fully vaccinated. SunSeeker Saturday #2

i wouldn't go that far. they don't put the mercury stuff in vaccines anymore rampartd Saturday #4

Stop it! Mercury (Thimerosal) in vaccines does NOT cause autism. SunSeeker Saturday #5

i don't think it ever did rampartd Saturday #6

A slightly more informative article on the same subject: LudwigPastorius Saturday #7

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