at one time I wanted to cut my toes off, the pain was so bad, but it only lasted about ??? minutes, felt longer I am sure...never since

The pain only happens when laying down...do not remember pain while sitting up?

The only thing that I have that sometimes works are two different muscle relaxers and Valium.


My PN comes from an autoimmune neuromuscular disease I have called Dermatomyositis. I was concerned at first that it was so severe I might lose a toe or two.

I won't take pain pills anymore so I'm holding out for medical cannabis when we vote on it this November.

Good luck.

and the tingles only remain at the very tip of my toes. Next, I'm going to try and get blood test for heavy metals and vitamin levels.

Also known as thiotic acid. Back when I was involved in some related stuff, it was a standard of care in Germany for neuropathy. Inexpensive and over-the-counter in the US.

Definitely don't take my word for it.

The best thing I have found to date is Lyrica. I am taking the max dosage though of 300 mg twice daily.

my kid had similar symptoms, but started with bad stomach, which was the first indication of porphyria.

My father often complained that he couldn't feel his feet when he got near 90, so genes may be involved. I also started taking lost of B-12 and that seems to be helping also. I do want to get a blood work up for heavy metals. I eat a lot of fish and worked in a toxic environment for 30 years.

I have Lupus. After a bad gall bladder infection, I developed new symptoms to add to the Lupus symptom zoo: itching, burning, pin pricks, stabbing pains along my arms, hands, back, and abdomen. My doc and I tried all kinds of medications, nothing worked until i started taking relatively high dosages of Lyrica (100 mg/night, 75 mg/day). It resulted in about a 95% reduction in neuropathy-related pain. It was a life-saver.

If it wasn't for my three best friends, Lyrica, Celebrex, and Plaquenil, I don't think I'd be alive because the pain from the neuropathy and myalgia was so bad.