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Yo_Mama_Been_Loggin

(136,313 posts) Sat Apr 18, 2026, 02:46 PM 14 hrs ago

Christina Applegate hospitalized as ongoing MS battle takes painful turn

Christina Applegate has reportedly been hospitalized amid her ongoing battle with Multiple Sclerosis (MS), a disease wherein the immune system attacks the protective layer around the nerves, leading to incredibly painful symptoms.

The 54-year-old, who announced her diagnosis to the world in 2021, was reportedly admitted to hospital in late March, according to TMZ. Christina's representative shared a statement in the wake of the news, which read: "I have no comment on whether she is in the hospital or what her medical treatments are."

"She's had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast," they concluded. It is unclear if Christina was hospitalized for reasons relating to her MS.

Her MeSsy podcast co-host, Jamie-Lynn Sigler, shared on March 31 that their podcast would be going on a brief hiatus as they were "both busy with our books coming out". Christina released her memoir, You With the Sad Eyes, on March 3.

https://www.msn.com/en-us/health/other/christina-applegate-hospitalized-as-ongoing-ms-battle-takes-painful-turn/ar-AA216Gqt

Didn't know they both had it. A woman from my neighborhood that I grew up with died from it.

My sympathies.

9 replies

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Christina Applegate hospitalized as ongoing MS battle takes painful turn (Original Post) Yo_Mama_Been_Loggin 14 hrs ago OP

lovely lady Skittles 14 hrs ago #1

Yes and she appears to be suffering from the worst type of MS. Marie Marie 13 hrs ago #2

she had breast cancer too Skittles 12 hrs ago #5

Does Jamie Lynn Sigler also have MS ? JI7 12 hrs ago #3

Yes LeftInTX 12 hrs ago #8

She presented on an award show a few years back BaronChocula 12 hrs ago #4

Yeah, I had something in my eye too... progressoid 12 hrs ago #9

Christina,, you are in my prayers for healing 🙏🏼💚 Clouds Passing 12 hrs ago #6

Damn. progressoid 12 hrs ago #7

Skittles

(172,164 posts)

1. lovely lady

Reply to Yo_Mama_Been_Loggin (Original post)

Sat Apr 18, 2026, 02:49 PM

14 hrs ago

wishing the best for her, dreadful disease

Marie Marie

(11,374 posts)

2. Yes and she appears to be suffering from the worst type of MS.

Reply to Skittles (Reply #1)

Sat Apr 18, 2026, 04:33 PM

13 hrs ago

You're right, MS is dreadful.

Skittles

(172,164 posts)

5. she had breast cancer too

Reply to Marie Marie (Reply #2)

Sat Apr 18, 2026, 04:57 PM

12 hrs ago

I mean, WTF, just awful.

JI7

(93,740 posts)

3. Does Jamie Lynn Sigler also have MS ?

Reply to Yo_Mama_Been_Loggin (Original post)

Sat Apr 18, 2026, 04:51 PM

12 hrs ago

LeftInTX

(34,547 posts)

8. Yes

Reply to JI7 (Reply #3)

Sat Apr 18, 2026, 05:29 PM

12 hrs ago

In January 2016, Sigler revealed that she was diagnosed with multiple sclerosis (MS) when she was 20 years old.[41] In 2000, while filming Campfire Stories in Hamburg, New Jersey, Sigler was paralyzed from the waist down for several days. This symptom turned out to be related to multiple sclerosis, but it was misdiagnosed as Lyme disease at the time.[42][43] In December 2023, Novartis hired Sigler to star in a TV commercial for their multiple sclerosis drug Kesimpta.[44] In January 2026, Sigler would notably show her real life MS condition to a television audience while playing a doctor with MS during a guest appearance on Grey's Anatomy, with Sigler noting in an interview with People that the guest appearance made her "not feeling like I have to hide anything about my physicality" and that it "allowed me to do my best work."[24][45] On January 1, 2026 Sigler was shown in an video she posted on her Instagram page to now be using a mobility scooter.[46][47]

BaronChocula

(4,629 posts)

4. She presented on an award show a few years back

Reply to Yo_Mama_Been_Loggin (Original post)

Sat Apr 18, 2026, 04:53 PM

12 hrs ago

It may have been the Emmys. She got a standing ovation when she came out. Unfortunately I missed most of it because I had something in my eye.

A friend co-wrote a movie about the Wonderland murders ("Wonderland" ) and Applegate lobbied hard for her part in the movie because she grew up on that street in the Hollywood Hills when everything went down.

Her podcast partner Ms. Sigler has done commercials for an MS pharm product.